Evolution of mutation rate and virulence among human retroviruses.

doi:10.1098/rstb.1994.0150

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Article

Evolution of mutation rate and virulence among human retroviruses.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 29 Nov 1994

Ewald P W

Abstract excerpt

High mutation rates are generally considered to be detrimental to the fitness of multicellular organisms because mutations untune finely tuned biological machinery. However, high mutation rates may be favoured by a need to evade an immune system that has been strongly stimulated to recognize thos...

Topics

Biological Evolution
Humans
Mutation
Retroviridae
Virulence

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