Article
Correlations of allelic imbalance of chromosome 14 with adverse prognostic parameters in 148 renal cell carcinomas.
Genes, chromosomes & cancer - 1 Dec 1996
Béroud C, Fournet J C, Jeanpierre C, Droz D, Bouvier R, Froger D, Chrétien Y, Maréchal J M, Weissenbach J, Junien C
Abstract excerpt
To investigate cumulative genetic alterations during development and progression of renal cell carcinoma (RCC), we examined DNAs that were isolated from 148 RCCs for allelic imbalance (AI) at four loci on chromosome arm 3p and at 26 loci on chromosome arm 14q by using polymorphic microsatellite m...
Topics
- Adult
- Alleles
- Carcinoma, Renal Cell
- Chromosome Mapping
- Chromosomes, Human, Pair 14
- Female
- Heterozygote
- Humans
- Kidney Neoplasms
- Male
- Middle Aged
- Polymerase Chain Reaction
- Prognosis