High-level expression of the bacterial opd gene in Drosophila melanogaster: improved inducible insecticide resistance.

doi:10.1111/j.1365-2583.1994.tb00173.x

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Article

High-level expression of the bacterial opd gene in Drosophila melanogaster: improved inducible insecticide resistance.

Insect molecular biology - 1 Nov 1994

Benedict M Q, Scott J A, Cockburn A F

Abstract excerpt

The bacterial parathion hydrolase gene (opd) was expressed in transformed D. melanogaster under the control of an hsp70 promoter. Transformed lines carrying chimaeric genes designed for either cytoplasmic or secretory expression exhibited high- or low-level heat-shock-inducible transient resistance to paraoxon respectively. Greatest levels of resistance occurred approximately 12-16 h after heat shock and well...

Topics

Animals
Aryldialkylphosphatase
Base Sequence
Blotting, Northern
Chromosome Mapping
Drosophila melanogaster
Esterases
Gene Expression
Genotype
Hot Temperature
Insecticide Resistance

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Mortality

Paraoxon

Parathion

Promoter Regions, Genetic

Transformation, Genetic

Source

Open in PubMed

Identifiers

PMID: 7704308
DOI: 10.1111/j.1365-2583.1994.tb00173.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7704308-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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