Article
Molecular characterization of homozygous (high HbA2) beta-thalassemia intermedia in Greece.
Pediatric hematology and oncology - 1 Jan 2000
Kanavakis E, Traeger-Synodinos J, Tzetis M, Metaxotou-Mavromati A, Ladis V, Kattamis C
Abstract excerpt
Homozygous beta-thalassemia is usually characterized by severe anemia requiring regular blood transfusion for survival. For homozygous patients with milder clinical manifestations and no dependence on transfusion therapy, the term thalassemia intermedia is usually applied. Genetic mechanisms that...
Topics
- Child
- Genotype
- Globins
- Homozygote
- Humans
- Mutation
- beta-Thalassemia