The molecular basis of normal HbA2 (type 2) beta-thalassemia in Greece.

Article

The molecular basis of normal HbA2 (type 2) beta-thalassemia in Greece.

Hematologic pathology - 1 Jan 1994

Tzetis M, Traeger-Synodinos J, Kanavakis E, Metaxotou-Mavromati A, Kattamis C

Abstract excerpt

Heterozygotes for beta-thalassemia usually have raised levels of HbA2, but in Greece about 5% of beta-thalassemia carriers are observed to have normal or borderline levels. It is postulated that such cases have mild beta+ thalassemia mutations or coinheritance of delta-thalassemia. We selected 18...

Topics

Base Sequence
Female
Globins
Greece
Hemoglobin A2
Heterozygote
Humans
Male
Molecular Sequence Data
Mutation
Phenotype
beta-Thalassemia

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.