Article
Apo E genotypes in multiple sclerosis, Parkinson's disease, schwannomas and late-onset Alzheimer's disease.
Molecular and cellular probes - 1 Dec 1994
Rubinsztein D C, Hanlon C S, Irving R M, Goodburn S, Evans D G, Kellar-Wood H, Xuereb J H, Bandmann O, Harding A E
Abstract excerpt
Apolipoprotein E (apo E) exists in three allelic, functionally distinct isoforms (apo E2, E3 and E4). Recent work has suggested that apo-E-dependent uptake of lipoproteins may play important roles in the development and maintenance of the nervous system and in the responses to both peripheral and...
Topics
- Alzheimer Disease
- Apolipoproteins E
- Brain Neoplasms
- Cholesterol
- Disease Susceptibility
- Female
- Genotype
- Humans
- Male
- Middle Aged
- Multiple Sclerosis
- Neurilemmoma
- Neurofibromatosis 2
- Parkinson Disease