Article
1,3-Butadiene: linking metabolism, dosimetry, and mutation induction.
Environmental health perspectives - 1 Nov 1994
Bond J A, Csanady G A, Gargas M L, Guengerich F P, Leavens T, Medinsky M A, Recio L
Abstract excerpt
There is increasing concern for the potential adverse health effects of human exposures to chemical mixtures. To better understand the complex interactions of chemicals within a mixture, it is essential to develop a research strategy which provides the basis for extrapolating data from single chemicals to their behavior within the chemical mixture. 1,3-Butadiene (BD) represents an interesting case study in which...
Topics
- Animals
- Bacteriophages
- Benzene
- Butadienes
- Drug Interactions
- Ethanol
- Humans
- Lung
- Male
- Mice
- Mice, Transgenic
- Microsomes