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Article

Quantitative trait loci mapping of genes that influence the sensitivity and tolerance to ethanol-induced hypothermia in BXD recombinant inbred mice.

The Journal of pharmacology and experimental therapeutics - 1 Apr 1994

Crabbe J C, Belknap J K, Mitchell S R, Crawshaw L I

Abstract excerpt

A recent method allows the identification of the rough genetic map location in mice of genes that exert modest effects on continuously distributed (i.e., quantitative) variables. Sensitivity and tolerance tolerance to the hypothermic effect of ethanol were studied with the purpose of identifying such quantitative trait loci (QTL). Mice from two progenitor inbred strains, C57BL/6J and DBA/2J, and 19 of their...

Topics

Animals
Chromosome Mapping
Drug Tolerance
Ethanol
Female
Genetic Linkage
Genetic Markers
Genotype
Hypothermia
Male
Mice

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice, Inbred C57BL

Mice, Inbred DBA

Mice, Inbred Strains

Polymorphism, Genetic

Sensitivity and Specificity

Source

Identifiers

PMID: 8169823

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8169823-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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