Article
[The peptide mapping of the E2-2 and E2-6 sites of the E2 glycoprotein in the Venezuelan equine encephalomyelitis virus].
Voprosy virusologii - 1 Jan 2000
Sviatchenko V A, Pereboev A V, Agapov E V, Razumov I A, Sabirov A N, Mizenko G A, Samukov V V, Loktev V B
Abstract excerpt
Nine peptides were synthesized for detailed mapping of VEE virus E2-2 and E2-6 sites responsible for the formation of protective antibodies that neutralize the virus and block hemagglutination. The sequence of the peptides over-lapped the regions of amino acid residues 30-75 and 202-250 of VEE vi...
Topics
- Amino Acid Sequence
- Animals
- Antibodies, Monoclonal
- Antigens, Viral
- Binding Sites, Antibody
- Encephalitis Virus, Venezuelan Equine
- Epitopes
- Hybridomas
- Immunization
- Immunologic Techniques
- Mice
- Mice, Inbred BALB C
- Molecular Sequence Data
- Mutation
- Peptide Mapping
- Peptides
- Rats
- Viral Envelope Proteins