Article
Monoclonal antibodies to the E2 protein of a new genotype (type 2) of bovine viral diarrhea virus define three antigenic domains involved in neutralization.
Virus research - 1 Oct 1998
Deregt D, van Rijn P A, Wiens T Y, van den Hurk J
Abstract excerpt
Bovine viral diarrhea virus (BVDV) has recently been segregated into two genotypes, namely, BVDV 1 and BVDV 2. Viruses of the BVDV 2 genotype are a cause of hemorrhagic and acute fatal disease in cattle in the US and Canada. In this study, monoclonal antibodies (mAbs) to the newly described BVDV...
Topics
- Amino Acid Sequence
- Animals
- Antibodies, Monoclonal
- Antibodies, Viral
- Antigens, Viral
- Bovine Virus Diarrhea-Mucosal Disease
- Cattle
- Diarrhea Virus 1, Bovine Viral
- Diarrhea Virus 2, Bovine Viral
- Epitope Mapping
- Genotype
- Immunodominant Epitopes
- Molecular Sequence Data
- Neutralization Tests
- Viral Envelope Proteins