Article
Neutralization determinants of laboratory strains and field isolates of equine arteritis virus: identification of four neutralization sites in the amino-terminal ectodomain of the G(L) envelope glycoprotein.
Virology - 26 May 1997
Balasuriya U B, Patton J F, Rossitto P V, Timoney P J, McCollum W H, MacLachlan N J
Abstract excerpt
The N-terminal hydrophilic ectodomain of the G(L) envelope glycoprotein of equine arteritis virus (EAV) contains neutralization determinants of the virus. We developed a panel of 17 neutralizing murine monoclonal antibodies (MAbs) to further characterize the neutralization determinants of EAV. In...
Topics
- Amino Acid Sequence
- Animals
- Antibodies, Monoclonal
- Cell Line
- Epitopes
- Equartevirus
- Immune Sera
- Molecular Sequence Data
- Neutralization Tests
- Open Reading Frames
- Phenotype