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Article

An interferon resistant variant of the hairy-cell leukemic cell line, Eskol: biochemical and immunological characterization.

Leukemia research - 1 Nov 1993

Ozes O N, Klein S B, Reiter Z, Taylor M W

Abstract excerpt

The B-lymphoblastoid cell line Eskol, which is composed of differentiated cells resembling hairy-cell leukemia, has been used to study the effects of type I interferon in vitro. In order to study the mechanism of delayed interferon therapy resistance, a hairy-cell leukemia-like clonal cell line (IREs-4) was isolated from Eskol after 4 months of exposure to r-metIFN-con1. When compared to Eskol cells, the IREs-4...

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PMID: 7694002
DOI: 10.1016/0145-2126(93)90046-n

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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