Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

In Vivo gp41 Antibodies Targeting the 2F5 Monoclonal Antibody Epitope Mediate Human Immunodeficiency Virus Type 1 Neutralization Breadth

5 Feb 2009

Abstract excerpt

The broadly neutralizing human monoclonal antibodies (MAbs) 2F5 and 4E10, both targeting the highly conserved human immunodeficiency virus type 1 (HIV-1) envelope membrane proximal external region (MPER), are among the MAbs with the broadest heterologous neutralizing activity and are of considerable interest for HIV-1 vaccine development. We have identified serum antibodies from an HIV-infected subject that both...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to HIV/AIDS drug development and treatment
Share to HIV Research and Treatment
Share to Immune Cell Function and Interaction

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19193787
DOI: 10.1128/jvi.02631-08

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

In Vivo gp41 Antibodies Targeting the 2F5 Monoclonal Antibody Epitope Mediate Human Immunodeficiency Virus Type 1 Neutralization BreadthPMID 19193787Read ↗

Factors Associated with the Development of Cross-Reactive Neutralizing Antibodies during Human Immunodeficiency Virus Type 1 InfectionSemantic proximity Read ↗

Epitope mapping of broadly neutralizing HIV-2 human monoclonal antibodies.Semantic proximity Read ↗

Targeting antibody responses to the membrane proximal external region of the envelope glycoprotein of human immunodeficiency virus.Semantic proximity Read ↗

Role of HIV membrane in neutralization by two broadly neutralizing antibodies.Semantic proximity Read ↗

In vivo and in vitro escape from neutralizing antibodies 2G12, 2F5, and 4E10.Semantic proximity Read ↗

Broadly Neutralizing Antibodies for HIV EradicationSemantic proximity Read ↗

Structure and Mechanistic Analysis of the Anti-Human Immunodeficiency Virus Type 1 Antibody 2F5 in Complex with Its gp41 EpitopeSemantic proximity Read ↗

A fusion-intermediate state of HIV-1 gp41 targeted by broadly neutralizing antibodiesSemantic proximity Read ↗

Antibodies Targeting the Envelope of HIV-1.Semantic proximity Read ↗

Rational Design of Envelope Identifies Broadly Neutralizing Human Monoclonal Antibodies to HIV-1Semantic proximity Read ↗

A conserved neutralizing epitope on gp41 of human immunodeficiency virus type 1Semantic proximity Read ↗

Bispecific Antibodies Targeting Different Epitopes on the HIV-1 Envelope Exhibit Broad and Potent NeutralizationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.