Article
Anomalous plasma concentrations and impaired secretion of growth factors in Fanconi's anemia.
Stem cells (Dayton, Ohio) - 1 Jul 1993
Wunder E, Mortensen B T, Schilling F, Hénon P R
Abstract excerpt
In Fanconi's anemia, which is known to be an autosomal recessive Mendelian trait with four complementary groups. In addition to stunning phenotypic variation at clinical and cellular levels, aplastic pancytopenia is a common feature. Since either an early block of differentiation in stem cells or...
Topics
- Adolescent
- Adult
- Cells, Cultured
- Child
- Fanconi Anemia
- Female
- Granulocyte-Macrophage Colony-Stimulating Factor
- Hematopoietic Cell Growth Factors
- Humans
- Interleukin-1
- Interleukin-6
- Macrophages
