Article
Abnormalities of cytokine receptor signalling contributing to diseases of red blood cell production.
Annals of medicine - 1 Jun 1999
Goyal R K, Longmore G D
Abstract excerpt
The production of erythroid cells is a dynamic and exquisitely regulated process. The mature red cell is only the final phase of a complex but orderly series of genetic events that are initiated at the time a multipotent stem cell becomes committed to expressing the erythroid programme. Aberrations either in the intrinsic generation and/or amplification of functional erythroid cells or in the regulatory...
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