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Article

Human immunodeficiency virus type-1 (HIV-1) infection of endothelial cells in vitro: a virological, ultrastructural and immuno-cytochemical approach.

Journal of submicroscopic cytology and pathology - 1 Apr 1992

Cenacchi G, Re M C, Preda P, Pasquinelli G, Furlini G, Apkarian R P, La Placa M, Martinelli G N

Abstract excerpt

In an attempt to better understand the role of endothelial cells during HIV-1 infection, we report a virological and ultrastructural study on isolated endothelial cells from human adipose tissue, infected by HIV-1 in vitro. Supernatants from cultures showed the presence of p24 antigen and reverse transcriptase activity starting two days after HIV inoculation. A significant decrease of viral rescue was observed in...

Topics

Adipose Tissue
Antigens, Surface
Cells, Cultured
Cycloheximide
Endothelium, Vascular
HIV Core Protein p24
HIV Infections
HIV Reverse Transcriptase
HIV-1
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenotype

RNA-Directed DNA Polymerase

Skin

Source

Identifiers

PMID: 1376212

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1376212-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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