Article
Maternal HIV type 1 infection suppresses MMP-1 expression in endothelial cells of uninfected newborns: nonviral vertical transmission of HIV type 1-related effects.
AIDS research and human retroviruses - 1 Nov 2005
Jörg Anita, Grubert Thomas, Grimm Thomas, Guenzi Eric, Naschberger Elisabeth, Samson Elenore, Oostendorp Robert, Keller Ulrich, Stürzl Michael
Abstract excerpt
HIV-1 infection is associated with vascular alterations. This is accompanied by an increased risk of cardiovascular diseases and Kaposi's sarcoma, an endothelial cell-derived tumor. We investigated the impact of maternal HIV-1 infection on phenotype and gene expression of endothelial cells in newborns. For this reason endothelial precursor cells and differentiated endothelial cells were isolated from cord blood...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
