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Article

Molecular characterisation of Vietnamese HPFH.

Human mutation - 1 Jan 1993

Motum P I, Hamilton T J, Lindeman R, Le H, Trent R J

Abstract excerpt

A novel 30 kb deletion of the beta-globin gene cluster associated with the phenotype of hereditary persistence of fetal hemoglobin (HPFH) is described in two unrelated individuals of Vietnamese background. The Vietnamese G gamma A gamma HPFH deletion has a unique 5' breakpoint 3.5 kb downstream of the delta-globin gene. The 3' breakpoint lies approximately 8 kb upstream from the HPFH-3 breakpoint (Henthorn et...

Topics

Adult
Base Sequence
DNA
Fetal Hemoglobin
Globins
Hemoglobinopathies
Humans
Molecular Sequence Data
Phenotype
Restriction Mapping
Sequence Deletion
Vietnam

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Identifiers

PMID: 7689901
DOI: 10.1002/humu.1380020305

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7689901-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Molecular characterisation of Vietnamese HPFH.PMID 7689901Read ↗

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