Article
Haptoglobin genotyping of Vietnamese: global distribution of HP del, complete deletion allele of the HP gene.
Legal medicine (Tokyo, Japan) - 1 Jan 2015
Soejima Mikiko, Agusa Tetsuro, Iwata Hisato, Fujihara Junko, Kunito Takashi, Takeshita Haruo, Lan Vi Thi Mai, Minh Tu Binh, Takahashi Shin, Trang Pham Thi Kim, Viet Pham Hung, Tanabe Shinsuke, Koda Yoshiro
Abstract excerpt
The haptoglobin (HP) gene deletion allele (HP(del)) is responsible for anhaptoglobinemia and a genetic risk factor for anaphylaxis reaction after transfusion due to production of the anti-HP antibody. The distribution of this allele has been explored by several groups including ours. Here, we studied the frequency of HP(del) in addition to the distribution of common HP genotypes in 293 Vietnamese. The HP(del) was...
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