Phenotypic modulation of human hair matrix cells (trichocytes) by environmental influence in vitro and in vivo.

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Article

Phenotypic modulation of human hair matrix cells (trichocytes) by environmental influence in vitro and in vivo.

Epithelial cell biology - 1 Apr 1993

Limat A, Breitkreutz D, Thiekoetter G, Noser F, Hunziker T, Braathen L R, Fusenig N E

Abstract excerpt

Trichocytes, i.e. precursor cells of the hair cortex and medulla, isolated from plucked human scalp hair follicles (HF) were propagated on feeder layers of post-mitotic human dermal fibroblasts (HDF). Cell isolates from five HF routinely yielded about 0.5-1 x 10(5) cells within 3 weeks. When grown as 'surface epithelia' in vitro (on dermal equivalents exposed to air), trichocytes organized into stratified...

Topics

Animals
Cell Division
Cells, Cultured
Collagen
Drug Combinations
Epidermal Cells
Fibroblasts
Filaggrin Proteins
Fluorescent Antibody Technique
Hair
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Immunohistochemistry

Keratins

Laminin

Mice

Mice, Nude

Mitosis

Phenotype

Source

Open in PubMed

Identifiers

PMID: 7689029

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7689029-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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