Article
Lineage determination of CD7+ CD5- CD2- and CD7+ CD5+ CD2- lymphoblasts: studies on phenotype, genotype, and gene expression of myeloperoxidase, CD3 epsilon, and CD3 delta.
American journal of hematology - 1 Apr 1994
Yoneda N, Tatsumi E, Teshigawara K, Nagata S, Nagano T, Kishimoto Y, Kimura T, Yasunaga K, Yamaguchi N
Abstract excerpt
The gene expression of myeloperoxidase (MPO), CD3 epsilon, and CD3 delta molecules, the gene rearrangement of T-cell receptor (TCR) delta, gamma, and beta and immunoglobulin heavy (IgH) chain, and the expression of cell-surface antigens were investigated in seven cases of CD7+ CD5- CD2- and four cases of CD7+ CD5+ CD2- acute lymphoblastic leukemia or lymphoblastic lymphoma (ALL/LBL) blasts, which were negative...
Topics
- Acute Disease
- Adolescent
- Adult
- Antigens, CD
- Antigens, CD7
- Antigens, Differentiation, T-Lymphocyte
- Blotting, Northern
- CD2 Antigens
- CD3 Complex
- CD5 Antigens