Article
Influenza A virus-specific H-2d restricted cross-reactive cytotoxic T lymphocyte epitope(s) detected in the hemagglutinin HA2 subunit of A/Udorn/72.
Virology - 20 Dec 1995
Saikh K U, Martin J D, Nishikawa A H, Dillon S B
Abstract excerpt
BALB/c mice immunized with a vaccinia virus recombinant expressing the influenza A virus (A/Udorn/72; subtype H3) hemagglutinin HA2 (H3HA2) induced a strong CD8+ cytotoxic T lymphocyte (CTL) response which was H-2d-restricted. Two peptides, derived from the primary sequence of the H3HA2 and consi...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Cell Line
- Chick Embryo
- Cross Reactions
- Epitopes, T-Lymphocyte
- Genetic Vectors
- H-2 Antigens
- Hemagglutinin Glycoproteins, Influenza Virus
- Hemagglutinins, Viral
- Humans
- Influenza A virus
- Mice
- Mice, Inbred BALB C
- Molecular Sequence Data
- Structure-Activity Relationship
- T-Lymphocytes, Cytotoxic