Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Influence of a single viral epitope on T cell response and disease after infection of mice with respiratory syncytial virus.

Journal of immunology (Baltimore, Md. : 1950) - 15 Dec 2007

Vallbracht Simone, Jessen Birthe, Mrusek Sonja, Enders Anselm, Collins Peter L, Ehl Stephan, Krempl Christine D

Abstract excerpt

CTL are important for virus clearance but also contribute to immunopathology after the infection of BALB/c mice with respiratory syncytial virus (RSV). The pulmonary immune response to RSV is dominated by a CTL population directed against the CTL epitope M2-1 82-90. Infection with a virus carrying an M2-1 N89A mutation introduced by reverse genetics failed to activate this immunodominant CTL population, leading...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epitopes, T-Lymphocyte
Share to Immunodominant Epitopes

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mice, Inbred BALB C

Share to Oligopeptides

Share to Receptors, Antigen, T-Cell

Share to Respiratory Syncytial Virus Infections

Share to Respiratory Syncytial Viruses

Share to T-Lymphocytes, Cytotoxic

Source

Identifiers

PMID: 18056370
DOI: 10.4049/jimmunol.179.12.8264

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Influence of a single viral epitope on T cell response and disease after infection of mice with respiratory syncytial virus.PMID 18056370Read ↗

Phenotype and Hierarchy of Two Transgenic T Cell Lines Targeting the Respiratory Syncytial Virus KdM282-90 Epitope Is Transfer Dose-Dependent.Semantic proximity Read ↗

Enhancement of the CD8+ T cell response to a subdominant epitope of respiratory syncytial virus by deletion of an immunodominant epitopeSemantic proximity Read ↗

Hierarchy among multiple H-2b-restricted cytotoxic T-lymphocyte epitopes within simian virus 40 T antigen.Semantic proximity Read ↗

Phenotypic and functional characterization of T cell lines specific for individual respiratory syncytial virus proteins.Semantic proximity Read ↗

Distinct types of lung disease caused by functional subsets of antiviral T cells.Semantic proximity Read ↗

Novel role of CD8(+) T cells and major histocompatibility complex class I genes in the generation of protective CD4(+) Th1 responses during retrovirus infection in mice.Semantic proximity Read ↗

T-cell receptors from virus-specific cytotoxic T lymphocytes recognizing a single immunodominant nine-amino-acid viral epitope show marked diversity.Semantic proximity Read ↗

Mapping and Characterization of the Primary and Anamnestic H-2 <sup>d</sup> -Restricted Cytotoxic T-Lymphocyte Response in Mice against Human MetapneumovirusSemantic proximity Read ↗

Analysis of the HLA-restricted influenza-specific cytotoxic T lymphocyte response in transgenic mice carrying a chimeric human-mouse class I major histocompatibility complex.Semantic proximity Read ↗

A single amino acid variation within an immunodominant AKR/Gross MuLV cytotoxic T-lymphocyte epitope leads to a loss in immunogenicity.Semantic proximity Read ↗

Conserved cysteine residues within the attachment G glycoprotein of respiratory syncytial virus play a critical role in the enhancement of cytotoxic T-lymphocyte responses.Semantic proximity Read ↗

Latency and Persistence of Respiratory Syncytial Virus Despite T Cell ImmunitySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.