Article
DNA fingerprinting of renal cell carcinoma with special reference to tumor heterogeneity.
Genes, chromosomes & cancer - 1 Feb 1993
Mehle C, Ljungberg B, Stenling R, Roos G
Abstract excerpt
Genomic alterations in renal cell carcinoma were investigated by DNA fingerprinting using the simple repetitive oligonucleotide probe (CAC)s. Nine of ten tumors showed somatic changes in the fingerprint pattern compared with constitutional DNA. The most consistent changes were deletions and/or de...
Topics
- Carcinoma, Renal Cell
- DNA Fingerprinting
- DNA, Neoplasm
- Genetic Variation
- Humans
- Kidney Neoplasms
- Methylation
- Oligonucleotide Probes