Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dietary supplements of antioxidants reduce hprt mutant frequency in splenocytes of aging mice.

Mutation research - 1 Oct 1995

Gaziev A I, Podlutsky AJa, Panfilov B M, Bradbury R

Abstract excerpt

The level of spontaneous and gamma-radiation-induced mutations in the hypoxanthine-guanine phosphoribosyl-transferase (hprt) locus as well as the decrease in frequency of these mutations in mice of various age pretreated with dietary supplements of an antioxidant mixture (vitamins C, E, beta-carotene, rutin, selenium, zinc) were studied in splenocytes of young (8-14-week-old) and aged (102-110-week-old) male...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aging
Share to Cells, Cultured
Share to Gamma Rays

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Hypoxanthine Phosphoribosyltransferase

Share to Mice, Inbred Strains

Share to Mutation

Share to Spleen

Source

Identifiers

PMID: 7565884
DOI: 10.1016/0921-8734(95)00013-v

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dietary supplements of antioxidants reduce hprt mutant frequency in splenocytes of aging mice.PMID 7565884Read ↗

[A vitamin-antioxidant diet decreases the level of chromosomal damages and the frequency of gene mutations in irradiated mice].Semantic proximity Read ↗

Rationale for using multiple antioxidants in protecting humans against low doses of ionizing radiationSemantic proximity Read ↗

Radiation-induced apoptosis in mouse lymphocytes is modified by a complex dietary supplement: the effect of genotype and gender.Semantic proximity Read ↗

[Effect of beta-carotene on 60Co-gamma-induced mutation at T-lymphocyte hypoxanthine-guanine phosphoribosyl transferase locus in rats].Semantic proximity Read ↗

The effects of short-term calorie restriction on mutations in the spleen cells of infant-irradiated mice.Semantic proximity Read ↗

Should supplemental antioxidant administration be avoided during chemotherapy and radiation therapy?Semantic proximity Read ↗

Ascorbic acid reduced mutagenicity at the HPRT locus in CHO cells against thermal neutron radiation.Semantic proximity Read ↗

Preventive effect of antioxidant on ultraviolet-induced skin cancer in miceSemantic proximity Read ↗

[Age-related increase in the frequency of spontaneous and gamma-radiation-induced HPRT-mutations in murine spleen lymphocytes].Semantic proximity Read ↗

Dietary fruit and vegetables protect against somatic mutation in vivo, but low or high intake of carotenoids does not.Semantic proximity Read ↗

The influence of smoking and diet on the hypoxanthine phosphoribosyltransferase (hprt) mutant frequency in circulating T lymphocytes from a normal human population.Semantic proximity Read ↗

Evidence that the radioprotector effect of ascorbic acid depends on the radiation dose rate.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.