Article
Hypercholesterolemia in five Israeli Christian-Arab kindreds is caused by the "Lebanese" allele at the low density lipoprotein receptor gene locus and by an additional independent major factor.
Human genetics - 1 Nov 1991
Oppenheim A, Friedlander Y, Dann E J, Berkman N, Schwartz S P, Leitersdorf E
Abstract excerpt
Segregation analyses were performed for plasma low density lipoprotein cholesterol (LDL-C), triglycerides (TG) and high density lipoprotein cholesterol (HDL-C) in five Christian Arab kindreds identified through probands with familial hypercholesterolemia. In this subset of the Christian Arab community, the results were consistent with major gene determination of LDL-C with allele frequency (q) of 0.042 (95%...
Topics
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Alleles
- Base Sequence
- Child
- Child, Preschool
- Christianity
- DNA
- Female
