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Article

Molecular analysis of lambda bio transducing phage produced by oxolinic acid-induced illegitimate recombination in vivo.

Genetics - 1 Jul 1995

Shimizu H, Yamaguchi H, Ikeda H

Abstract excerpt

To study the mechanism of DNA gyrase-mediated illegitimate recombination in Escherichia coli, we examined the formation of lambda Spi- phage during prophage induction. The frequency of Spi- phage was two to three orders of magnitude higher in the presence of oxolinic acid, an inhibitor of DNA gyrase A subunit, than in the absence of the drug, while it was very low in nalAr bacteria with the drug. RecA function is...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 7672589
DOI: 10.1093/genetics/140.3.889
PMCID: PMC1206673

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Source receipt: pubmed, retrieved 7 Sept 2026.

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