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<i>Hxt</i> encodes a basic helix-loop-helix transcription factor that regulates trophoblast cell development

1 Aug 1995

Abstract excerpt

Trophoblast cells are the first lineage to form in the mammalian conceptus and mediate the process of implantation. We report the cloning of a basic helix-loop-helix (bHLH) transcription factor gene, Hxt, that is expressed in early trophoblast and in differentiated giant cells. A separate gene, Hed, encodes a related protein that is expressed in maternal deciduum surrounding the implantation site. Overexpression...

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PMID: 7671815
DOI: 10.1242/dev.121.8.2513

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