Article
Apolipoprotein E4 phenotype is not an important risk factor for coronary heart disease or stroke in elderly subjects.
Arteriosclerosis, thrombosis, and vascular biology - 1 Sept 1995
Kuusisto J, Mykkänen L, Kervinen K, Kesäniemi Y A, Laakso M
Abstract excerpt
The allele e4 (apo e4) of apolipoprotein E (apo E) has been associated with an increased risk for coronary heart disease (CHD) in cross-sectional studies in middle-aged subjects. We investigated the risk of CHD and stroke with respect to the number of apo e4 alleles in a prospective study of a Fi...
Topics
- Aged
- Alleles
- Apolipoprotein E4
- Apolipoproteins B
- Apolipoproteins E
- Cerebrovascular Disorders
- Cholesterol
- Cholesterol, LDL
- Coronary Disease
- Female
- Finland
- Gene Frequency
- Humans
- Male
- Phenotype
- Prospective Studies
- Risk Factors