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Article

Apolipoprotein E4 phenotype is not an important risk factor for coronary heart disease or stroke in elderly subjects.

Arteriosclerosis, thrombosis, and vascular biology - 1 Sept 1995

Kuusisto J, Mykkänen L, Kervinen K, Kesäniemi Y A, Laakso M

Abstract excerpt

The allele e4 (apo e4) of apolipoprotein E (apo E) has been associated with an increased risk for coronary heart disease (CHD) in cross-sectional studies in middle-aged subjects. We investigated the risk of CHD and stroke with respect to the number of apo e4 alleles in a prospective study of a Finnish nondiabetic cohort including 1067 subjects 65 to 74 years old at baseline. During the 3.5-year follow-up, CHD...

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Identifiers

PMID: 7670939
DOI: 10.1161/01.atv.15.9.1280

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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