Article
Different sensitivity to cell killing and chromosome mutation induction by gamma rays in two human lymphoblastoid cell lines derived from a single donor: possible role of apoptosis.
Mutagenesis - 1 May 1995
Schwartz J L, Jordan R, Sedita B A, Swenningson M J, Banáth J P, Olive P L
Abstract excerpt
The gamma-ray sensitivity of two human lymphoblastoid cell lines, TK6 and WI-L2-NS, was studied; both cell lines are derived from the same parent, WI-L2. TK6 was more sensitive to the cytotoxic effects of gamma rays, but showed fewer induced chromosome aberrations. There was no difference between...
Topics
- Apoptosis
- B-Lymphocytes
- Cell Cycle
- Cell Death
- Cell Line
- Cell Survival
- Chromosome Aberrations
- DNA Repair
- Gamma Rays
- Humans
- Mutagenicity Tests
- Mutation
- Radiation Tolerance
- Time Factors