SFL production by carcinoma cells induces the aggressive properties of nonproducing cells in vivo via a community effect.

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Article

SFL production by carcinoma cells induces the aggressive properties of nonproducing cells in vivo via a community effect.

Invasion & metastasis - 1 Jan 2000

Bellusci S, Moens G, Delouvée A, Thiery J P, Jouanneau J

Abstract excerpt

A metastatic rat bladder carcinoma cell line, M-NBT-II, produces and secretes a dissociating factor called SFL, whereas the tumorigenic parental cell line from which it originated (E-NBT-II) does not. In this work, we report that SFL production is correlated with an invasive phenotype in three-di...

Topics

Animals
Cell Communication
Collagen
Disease Progression
Female
Gelatinases
Hepatocyte Growth Factor
Mice
Mice, Nude
Neoplasm Transplantation
Phenotype
Plastics
Rats
Tumor Cells, Cultured
Urinary Bladder Neoplasms

Source

Open in PubMed

Identifiers

PMID: 7657525

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7657525-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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