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Article

Trypsin complexed with alpha 1-proteinase inhibitor has an increased structural flexibility.

FEBS letters - 21 Aug 1995

Kaslik G, Patthy A, Bálint M, Gráf L

Abstract excerpt

Mutant rat trypsin Asp189Ser was prepared and complexed with highly purified human alpha 1-proteinase inhibitor. The complex formed was purified to homogeneity and studied by N-terminal amino acid sequence analysis and limited proteolysis with bovine trypsin. As compared to uncomplexed mutant trypsin, the mutant enzyme complexed with alpha 1-proteinase inhibitor showed a highly increased susceptibility to...

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Identifiers

PMID: 7656972
DOI: 10.1016/0014-5793(95)00816-r

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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