Article
Monoallelic expression of IGF2 at the human fetal/maternal boundary.
Molecular reproduction and development - 1 Jun 1995
Ekström T J, Cui H, Nyström A, Rutanen E M, Ohlsson R
Abstract excerpt
IGF2 is expressed in both placental and decidual tissues, enabling an analysis of the parental imprinting over the fetomaternal boundary. Evidence is provided that IGF2 is monoallelically expressed in both placenta and pregnant, as well as nonpregnant, endometrium. These observations suggest that the maternally derived IGF2 allele is inactivated during germline transmission. Comparison of promoter usage in...
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