Article
Parental genomic imprinting of the human IGF2 gene.
Nature genetics - 1 May 1993
Giannoukakis N, Deal C, Paquette J, Goodyer C G, Polychronakos C
Abstract excerpt
The mouse igf2 gene, coding for the insulin-like growth factor II (IGF-II) is parentally imprinted, only the gene copy derived from the father is expressed. To know whether IGF2, the human homologue, is also imprinted, we used an ApaI polymorphism at the 3' untranslated region in order to distinguish between mRNA derived from each copy of the gene in placentae from heterozygote human fetuses, studied after...
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