Parental genomic imprinting of the human IGF2 gene.

doi:10.1038/ng0593-98

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Article

Parental genomic imprinting of the human IGF2 gene.

Nature genetics - 1 May 1993

Giannoukakis N, Deal C, Paquette J, Goodyer C G, Polychronakos C

Abstract excerpt

The mouse igf2 gene, coding for the insulin-like growth factor II (IGF-II) is parentally imprinted, only the gene copy derived from the father is expressed. To know whether IGF2, the human homologue, is also imprinted, we used an ApaI polymorphism at the 3' untranslated region in order to disting...

Topics

Alleles
Animals
Base Sequence
Deoxyribonucleases, Type II Site-Specific
Gene Expression Regulation
Gestational Age
Heterozygote
Humans
Insulin-Like Growth Factor II
Mice
Molecular Sequence Data
Parents
Placenta
Polymorphism, Restriction Fragment Length
Prader-Willi Syndrome
RNA, Messenger
Species Specificity

Source

Open in PubMed

Identifiers

PMID: 8099843
DOI: 10.1038/ng0593-98

Genes

IGF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8099843-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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