Article
Detection of rare allelic variants of the interferon-alpha 2 gene in human genomic DNA.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research - 1 May 1995
Gewert D R, Sharp N A, Barber K A, Cooper H, Tucker D, Lewis A P, Thursz M, Crowe J S
Abstract excerpt
We have analyzed human donor DNA for the presence of sequences corresponding to allelic variants of the IFN-alpha 2 locus. Using both restriction enzyme digestion of PCR-amplified fragments and sequence analysis of these fragments, we have identified the three reported allelic variants, IFN-alpha 2a, IFN-alpha 2b, and IFN-alpha 2c, in genomic DNA derived from donors of African or Afro-Caribbean origin. This is...
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