Article
Detection of rare allelic variants of the interferon-alpha 2 gene in human genomic DNA.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research - 1 May 1995
Gewert D R, Sharp N A, Barber K A, Cooper H, Tucker D, Lewis A P, Thursz M, Crowe J S
Abstract excerpt
We have analyzed human donor DNA for the presence of sequences corresponding to allelic variants of the IFN-alpha 2 locus. Using both restriction enzyme digestion of PCR-amplified fragments and sequence analysis of these fragments, we have identified the three reported allelic variants, IFN-alpha...
Topics
- Alleles
- Base Sequence
- DNA
- Genetic Variation
- Genome, Human
- Humans
- Interferon Type I
- Interferon alpha-2
- Interferon-alpha
- Molecular Sequence Data
- Polymerase Chain Reaction
- Recombinant Proteins
- Restriction Mapping