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Article

High-efficiency retroviral-mediated gene transfer into human and nonhuman primate peripheral blood lymphocytes.

15 Aug 1995

Abstract excerpt

Peripheral blood lymphocytes (PBLs) are primary targets for gene therapy of inherited and acquired disorders of the immune system. We describe the development of an optimized transduction system that provides for high-efficiency retrovirus-mediated gene transfer into primary PBLs. This optimized transduction protocol combines centrifugation of the lymphocytes (1000 x g) at the inception of transduction with...

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Identifiers

PMID: 7644487
DOI: 10.1073/pnas.92.17.7739

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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