Article
Peripheral blood lymphocytes as target cells of retroviral vector- mediated gene transfer
1 Apr 1994
Abstract excerpt
Peripheral blood lymphocytes (PBLs) are key target cells for gene therapy of a number of inherited and acquired blood disorders. We have systematically compared four retroviral vectors, designed according to different strategies, for their efficiency in transfer and expression in human PBLs of the same reporter gene. The receptor gene used in the study codes for the human low-affinity nerve growth factor receptor...
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