A truncated form of the Pho80 cyclin redirects the Pho85 kinase to disrupt vacuole inheritance in S. cerevisiae.

doi:10.1083/jcb.130.4.835

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Article

A truncated form of the Pho80 cyclin redirects the Pho85 kinase to disrupt vacuole inheritance in S. cerevisiae.

The Journal of cell biology - 1 Aug 1995

Nicolson T A, Weisman L S, Payne G S, Wickner W T

Abstract excerpt

Partitioning of the vacuole during cell division in Saccharomyces cerevisiae begins during early S phase and ends in late G2 phase before the yeast nucleus migrates into the bud neck. We have isolated and characterized a new mutant, vac5-1, which is defective in vacuole segregation. Cells with the vac5-1 mutation can form large buds without vacuoles. The VAC5 gene was cloned and is identical to PHO80. PHO80...

Topics

Alleles
Amino Acid Sequence
Base Sequence
Carboxypeptidases
Cathepsin A
Cell Division
Cyclin-Dependent Kinases
Cyclins
DNA-Binding Proteins
Extrachromosomal Inheritance
Fungal Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Homeodomain Proteins

Molecular Sequence Data

Mutation

Phosphates

Protein Processing, Post-Translational

Repressor Proteins

Saccharomyces cerevisiae

Source

Open in PubMed Open full text

Identifiers

PMID: 7642701
DOI: 10.1083/jcb.130.4.835
PMCID: PMC2199970

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7642701-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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A truncated form of the Pho80 cyclin redirects the Pho85 kinase to disrupt vacuole inheritance in S. cerevisiae.PMID 7642701Read ↗

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