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Article

A truncated form of the Pho80 cyclin redirects the Pho85 kinase to disrupt vacuole inheritance in S. cerevisiae.

The Journal of cell biology - 1 Aug 1995

Nicolson T A, Weisman L S, Payne G S, Wickner W T

Abstract excerpt

Partitioning of the vacuole during cell division in Saccharomyces cerevisiae begins during early S phase and ends in late G2 phase before the yeast nucleus migrates into the bud neck. We have isolated and characterized a new mutant, vac5-1, which is defective in vacuole segregation. Cells with the vac5-1 mutation can form large buds without vacuoles. The VAC5 gene was cloned and is identical to PHO80. PHO80...

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Identifiers

PMID: 7642701
DOI: 10.1083/jcb.130.4.835
PMCID: PMC2199970

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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A truncated form of the Pho80 cyclin redirects the Pho85 kinase to disrupt vacuole inheritance in S. cerevisiae.PMID 7642701Read ↗

Dissection of a complex phenotype by functional genomics reveals roles for the yeast cyclin-dependent protein kinase Pho85 in stress adaptation and cell integrity.Semantic proximity Read ↗

Regulation of the Pcl7-Pho85 cyclin-cdk complex by Pho81.Semantic proximity Read ↗

A genetic study of signaling processes for repression of PHO5 transcription in Saccharomyces cerevisiae.Semantic proximity Read ↗

A systematic high-throughput screen of a yeast deletion collection for mutants defective in PHO5 regulation.Semantic proximity Read ↗

Chemical inhibition of the Pho85 cyclin-dependent kinase reveals a role in the environmental stress response.Semantic proximity Read ↗

Deletion of the gene encoding the cyclin-dependent protein kinase Pho85 alters glycogen metabolism in Saccharomyces cerevisiae.Semantic proximity Read ↗

Vac7p, a novel vacuolar protein, is required for normal vacuole inheritance and morphology.Semantic proximity Read ↗

The identification of Pcl1-interacting proteins that genetically interact with Cla4 may indicate a link between G1 progression and mitotic exit.Semantic proximity Read ↗

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