Article
Polymorphic paracetamol conjugation: phenotyping in a Hungarian population.
Acta medica Hungarica - 1 Jan 1994
Róna K, Ary K, Szüts I, Kovács L, Gachályi B
Abstract excerpt
The authors studied the distribution of the paracetamol conjugation in a Hungarian population (53 adult Caucasian persons). The data indicated that the excretion of paracetamol glucuronide and sulphate were not normally distributed. Bimodality were apparent in both conjugation pathways: 15.1% of subjects was relatively extensive glucuronidators, and the 24.5% of subjects was extensive sulphatators. Monitoring the...
Topics
- Acetaminophen
- Administration, Oral
- Adult
- Age Factors
- Chromatography, Liquid
- Female
- Glucuronates
- Humans
- Hungary
- Male
- Phenotype
- Sulfates