Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Minoxidil sulphation in human liver and platelets. A study of interindividual variability.

European journal of clinical pharmacology - 1 Jan 1993

Pacifici G M, Bigotti R, Marchi G, Giuliani L

Abstract excerpt

Minoxidil requires to be sulphated to exert its hypotensive effect. We report on interindividual variability in the rate of minoxidil sulphation in 118 specimens of human liver and in platelets obtained from 100 healthy subjects and 100 newborns. The frequency distribution histogram of the hepatic activity of minoxidil sulphotransferase was positively skewed; the mean was 631 pmol.min-1 x mg-1. After logarithmic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Aged, 80 and over
Share to Blood Platelets

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Infant, Newborn

Share to Phenotype

Source

Identifiers

PMID: 8299666
DOI: 10.1007/BF00265951

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 10 closest

Minoxidil sulphation in human liver and platelets. A study of interindividual variability.PMID 8299666Read ↗

Interindividual variability in acetaminophen sulfation by human fetal liver: Implications for pharmacogenetic investigations of drug‐induced birth defectsSemantic proximity Read ↗

Human phenol sulfotransferases SULT1A2 and SULT1A1: genetic polymorphisms, allozyme properties, and human liver genotype-phenotype correlations.Semantic proximity Read ↗

Phenotype-genotype relationships of SULT1A1 in human liver and variations in the IC50 of the SULT1A1 inhibitor quercetin.Semantic proximity Read ↗

On the role of genetic polymorphisms in the sulfation of cholesterol by human cytosolic sulphotransferase SULT2B1b.Semantic proximity Read ↗

Frequency distribution of phenol sulfotransferase 1A1 activity in platelet cells from healthy Japanese subjects.Semantic proximity Read ↗

Sulfation of apomorphine by human sulfotransferases: evidence of a major role for the polymorphic phenol sulfotransferase, SULT1A1.Semantic proximity Read ↗

Characterization of human liver thermostable phenol sulfotransferase (SULT1A1) allozymes with 3,3',5-triiodothyronine as the substrate.Semantic proximity Read ↗

Polymorphic paracetamol conjugation: phenotyping in a Hungarian population.Semantic proximity Read ↗

Involvement of cytochrome P450 and the flavin-containing monooxygenase(s) in the sulphoxidation of simple sulphides in human liver microsomes.Semantic proximity Read ↗

Polymorphic distribution of glutathione transferase activity with methyl chloride in human blood.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.