Minoxidil sulphation in human liver and platelets. A study of interindividual variability.

doi:10.1007/BF00265951

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Article

Minoxidil sulphation in human liver and platelets. A study of interindividual variability.

European journal of clinical pharmacology - 1 Jan 1993

Pacifici G M, Bigotti R, Marchi G, Giuliani L

Abstract excerpt

Minoxidil requires to be sulphated to exert its hypotensive effect. We report on interindividual variability in the rate of minoxidil sulphation in 118 specimens of human liver and in platelets obtained from 100 healthy subjects and 100 newborns. The frequency distribution histogram of the hepati...

Topics

Adult
Aged
Aged, 80 and over
Blood Platelets
Female
Humans
Infant, Newborn
Liver
Male
Middle Aged
Minoxidil
Phenotype
Sulfotransferases

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