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Article

Human cell mutants with very low mitochondrial DNA copy number (rho d).

Human molecular genetics - 1 May 1995

Vaillant F, Nagley P

Abstract excerpt

Mutants of human Namalwa cells are described, denoted rho d (mtDNA-depleted), which contain a very low mtDNA copy number. Three isolates, denoted FV02, FV03 and FV05, each selected on the basis of their pyruvate-dependent phenotype, were shown to have severely reduced mitochondrial respiratory functions consistent with results of histochemical and cytochrome analysis. Analyses of mtDNA by the polymerase chain...

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Identifiers

PMID: 7633451
DOI: 10.1093/hmg/4.5.903

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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