Article
Severe neonatal neutropenia due to anti-human leucocyte antigen B49 alloimmunization only: a case report.
Transfusion medicine (Oxford, England) - 1 Aug 2003
Tomicić M, Starcević M, Bux J, Zach V, Hundrić-Haspl Z, Drazić V, Grahovac B
Abstract excerpt
Alloimmune neonatal neutropenia (ANN) is a rare but potentially life-threatening disorder of neonates. Demonstration of alloantibodies against granulocyte-specific antigens shared by neonatal and paternal granulocytes in the maternal serum is essential in the diagnosis of ANN. In contrast to granulocyte-specific alloantibodies, the significance of human leucocyte antigen (HLA) class I antibodies for ANN is still...
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