Article
Hsp78, a Clp homologue within mitochondria, can substitute for chaperone functions of mt-hsp70.
The EMBO journal - 17 Jul 1995
Schmitt M, Neupert W, Langer T
Abstract excerpt
Hsp78 is a Clp homologue within mitochondria of Saccharomyces cerevisiae. Deletion of HSP78 does not cause any detectable changes in wild type cells, but results in a petite phenotype in the ssc1-3 mutant strain carrying a temperature-sensitive allele of mt-hsp70. When overexpressed in the ssc1-3 mutant strain, hsp78 suppresses the defect in mitochondrial protein import under permissive conditions in vitro and...
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