Article
A rat monoclonal anti-(human CD2) and L-leucine methyl ester impacts on human/SCID mouse graft and B lymphoproliferative syndrome.
Cancer immunology, immunotherapy : CII - 1 Jun 1995
Bombil F, Kints J P, Havaux X, Scheiff J M, Bazin H, Latinne D
Abstract excerpt
The transfer of human peripheral blood mononuclear cells (hu-PBMC) from adult Epstein-Barr-virus(EBV)-seropositive donors in SCID (severe combined immunodeficiency) mice frequently leads to the development of a human B lymphoproliferative syndrome (hu-BLPS). Therefore, as 90% of adult potential d...
Topics
- Animals
- Antibodies, Monoclonal
- B-Lymphocytes
- Blood Component Transfusion
- CD2 Antigens
- Chimera
- Humans
- Leucine
- Leukocytes, Mononuclear
- Lymphoproliferative Disorders
- Mice
- Mice, SCID
- Phenotype
- T-Lymphocytes
- Transplantation Chimera