Gene--environment interactions in the application of biomarkers of cancer susceptibility in epidemiology.

Article

Gene--environment interactions in the application of biomarkers of cancer susceptibility in epidemiology.

IARC scientific publications - 1 Jan 1997

Garte S, Zocchetti C, Taioli E

Abstract excerpt

Metabolic susceptibility genes are important determinants of individual susceptibility to the effects of environmental carcinogens. These genes follow the form of 'type 2' gene-environment interaction, whereby the polymorphic genetic risk factor functions only in the presence of an environmental...

Topics

Biomarkers, Tumor
Carcinogens
Disease Susceptibility
Environmental Exposure
Genetic Predisposition to Disease
Humans
Logistic Models
Models, Genetic
Neoplasms

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