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Article

Gene--environment interactions in the application of biomarkers of cancer susceptibility in epidemiology.

IARC scientific publications - 1 Jan 1997

Garte S, Zocchetti C, Taioli E

Abstract excerpt

Metabolic susceptibility genes are important determinants of individual susceptibility to the effects of environmental carcinogens. These genes follow the form of 'type 2' gene-environment interaction, whereby the polymorphic genetic risk factor functions only in the presence of an environmental exposure. Two different effects of carcinogen dose have been observed for these genes. Sometimes, increasing dose leads...

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PMID: 9354924

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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