Article
Relationship between insulin-dependent diabetes mellitus (IDDM) and non-insulin-dependent diabetes mellitus: beta-cell function, islet cell antibody, and haptoglobin in parents of IDDM patients.
Metabolism: clinical and experimental - 1 Jul 1995
Kajio H, Kobayashi T, Nakanishi K, Okubo M, Tsukada T, Nakayama T, Yamada N, Murase T, Yazaki Y, Kosaka K
Abstract excerpt
To examine the relationship between non-insulin-dependent diabetes mellitus (NIDDM) and insulin-dependent diabetes mellitus (IDDM), we studied beta-cell function, HLA type, and serologic markers of IDDM and NIDDM in the parents of IDDM patients. Fifty-two parents of 33 IDDM patients were examined in terms of islet-cell antibody (ICA) status, haptoglobin phenotype, HLA type, and insulin responses during an oral...
Topics
- Adult
- Aged
- Autoantibodies
- Blood Glucose
- Diabetes Mellitus, Type 1
- Diabetes Mellitus, Type 2
- Female
- Glucose Tolerance Test
- HLA Antigens
- Haplotypes