Article
Microglia in colony-stimulating factor 1-deficient op/op mice.
Journal of neuroscience research - 1 Mar 1995
Blevins G, Fedoroff S
Abstract excerpt
Mice that are homozygous for the autosomal recessive mutation osteopetrosis (op) suffer from a general skeletal sclerosis, and the numbers of macrophages in various tissues are significantly decreased. We report that microglia in op/op mice are not affected by the mutation. They have normal morphology and are present in the CNS in normal frequency. In cultures, disaggregated cells of neopallia can form microglia,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
