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Article

Linkage between obesity and a marker near the tumor necrosis factor-alpha locus in Pima Indians.

1 Jul 1995

Abstract excerpt

Because tumor necrosis factor-alpha (TNF-alpha) expression is increased in adipose tissue of both rodent models of obesity and obese humans, it has been considered as a candidate gene for obesity. Pima Indians were scored for genotypes at three polymorphic dinucleotide repeat loci (markers) near the gene TNF-alpha at 6p21.3. In a sib-pair linkage analysis, percent body fat, as measured by hydrostatic weighing,...

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PMID: 7615786
DOI: 10.1172/jci118016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Linkage between obesity and a marker near the tumor necrosis factor-alpha locus in Pima Indians.PMID 7615786Read ↗

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