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Article

Hemodynamic forces are complex regulators of endothelial gene expression

1 Jul 1995

Abstract excerpt

Vascular endothelial cells, by virtue of their unique anatomical position, are constantly exposed to the fluid mechanical forces generated by flowing blood. In vitro studies with model flow systems have demonstrated that wall shear stresses can modulate various aspects of endothelial structure and function. Certain of these effects appear to result from the regulation of expression of endothelial genes at the...

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PMID: 7615157
DOI: 10.1096/fasebj.9.10.7615157

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