Structure/function analysis of human interleukin 5 and its receptor.

doi:10.1007/978-3-0348-7276-8_3

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Article

Structure/function analysis of human interleukin 5 and its receptor.

Agents and actions. Supplements - 1 Jan 1995

Tavernier J, Cornelis S, Devos R, Guisez Y, Plaetinck G, Van der Heyden J

Abstract excerpt

We have performed a detailed structure-function analysis of human interleukin 5 (hIL5) and its receptor. By testing a hIL5 mutant panel in a solid phase binding assay and a proliferation assay using hIL5 dependent cell-lines, areas on hIL5 involved in either the receptor alpha-subunit interaction...

Topics

Animals
Humans
Interleukin-5
Mice
Molecular Structure
Mutation
Peptide Fragments
Receptors, Interleukin
Receptors, Interleukin-5
Structure-Activity Relationship

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